{"product_id":"albomed-standard-1-x-2ml","title":"Albomed Standard 1x 2.0 ml","description":"\u003cp\u003e\u003ca title=\"Albomed | Gelenkspritzen | StakonMed\" href=\"https:\/\/stakonmed.de\/collections\/albomed\"\u003e\u003cspan\u003eKD Intra-Articular\u003c\/span\u003e\u003cspan\u003e® \u003c\/span\u003e\u003c\/a\u003e\u003cspan\u003e\u003ca title=\"Albomed | Gelenkspritzen | StakonMed\" href=\"https:\/\/stakonmed.de\/collections\/albomed\"\u003eGel\u003c\/a\u003e\u003cbr\u003eKD Intra-Articular\u003c\/span\u003e\u003cspan\u003e® \u003c\/span\u003e\u003cspan\u003eUltra One Gel\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eSodium hyaluronate intra-articular\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDescription\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eThe product contains a prefilled syringe with hydrogel made of highly purified sodium hyaluronate obtained by bacterial fermentation without \u003c\/span\u003e\u003cspan\u003esodium hyaluronate obtained from genetic modifications with high molecular weight, which is used to improve \u003c\/span\u003e\u003cspan\u003eserves the viscosity in the intra-articular connective tissue. It has undergone steam sterilization for injectable products and is non-pyrogenic.\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eDepending on the product variant and concentration, 1 ml of aqueous, physiological phosphate buffer solution contains 10 mg, \u003c\/span\u003e\u003cspan\u003e16 mg, 22 mg, 25 mg or 30 mg sodium hyaluronate. The sodium hyaluronate hydrogel is in a weak, sterile, isotonic, and apyrogenic phosphate-buffered saline solution with a pH value \u003c\/span\u003e\u003cspan\u003efrom 7.2 (6.8 – 7.4) in sufficient volume for injection. Fill volumes vary depending on the variant from 1 to 4.8 ml. The translation of the chemical components is listed in the table in English (weight per volume as \u003c\/span\u003e\u003cspan\u003emg substance per 1 ml hydrogel):\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003e(a) Sodium hyaluronate, (b) Sodium chloride, (c) Disodium hydrogen phosphate 2 H\u003c\/span\u003e\u003cspan\u003e2\u003c\/span\u003e\u003cspan\u003eO,\u003cbr\u003e(d) Sodium dihydrogen phosphate 2 H\u003c\/span\u003e\u003cspan\u003e2\u003c\/span\u003e\u003cspan\u003eO, (e) Water for injection purposes\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eProperties and mode of action\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eAn essential component of healthy synovial fluid is the widespread glycosaminoglycan hyaluronic acid. \u003c\/span\u003e\u003cspan\u003eThis natural biopolymer provides viscoelasticity and, thanks to its lubricating and shock-absorbing properties, enables pain-free physiological movements; it also supplies nutrients to the cartilage. The \u003c\/span\u003e\u003cspan\u003eKD Intra-Articular\u003c\/span\u003e\u003cspan\u003e® \u003c\/span\u003e\u003cspan\u003eGel \u003c\/span\u003e\u003cspan\u003eThe contained sodium hyaluronate is a salt of hyaluronic acid.\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eIndications\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003ePain and limitation of joint mobility in degenerative changes of the knee joint and other synovial joints, including osteoarthritis.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eContraindications\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eThe product must not be used in patients\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003e- with known hypersensitivity to any of the components\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003e- with inflammation in the joint\u003cbr\u003e- with septic arthritis\u003cbr\u003e- with skin infections or skin diseases in the injection area\u003cbr\u003e- with natural or medication-induced coagulation disorders such as hemophilia or under use\u003c\/span\u003e\u003cspan\u003euse of anticoagulants such as Marcumar (phenprocoumon) or Coumadin (warfarin)\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eSince there are no clinical data on the use of hyaluronic acid in children, pregnant or breastfeeding women, use in these patients is not recommended.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003ePrecautions\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eSince septic arthritis can be a serious complication of treatment, please observe all precautions usually necessary for surgical procedures. Injections of the hydrogel must be administered directly into the joint cavity; injections into blood vessels and surrounding tissue must be avoided. Do not use if the prefilled syringe or sterile packaging is damaged.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 0.875rem;\"\u003eThe opened product must not be resterilized, resealed, or reused. It is intended for use by a single patient at a single treatment session.\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003ePossible side effects\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eNo adverse effects were observed in biocompatibility tests with the product. In the treated\u003c\/span\u003e\u003cspan\u003e- affected joint, local symptoms such as pain, redness, warmth, and swelling may occur. \u003c\/span\u003e\u003cspan\u003eThese symptoms can be reduced if the treated area is cooled with an ice pack for 5 to 10 minutes after injection. During the first days of treatment, the simultaneous oral intake of pain and anti-inflammatory medications (NSAIDs) may be beneficial. In cases of intense \u003c\/span\u003e\u003cspan\u003eIf pain or inflammation occurs, treatment should be discontinued. Treatment of adverse reactions should only be carried out under the supervision of the attending physician. Immediately after the injection, strenuous physical activity should be avoided and other instructions from the doctor should be followed. Medical personnel should inform the patient\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003e- about possible adverse events related to the product.\u003cbr\u003e- that the patient must report any adverse event or complication to a doctor. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePharmacological and chemical interactions\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eSo far, there are no data on the incompatibility of the product with other solutions for intra-articular use.\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eThere is a chemical incompatibility between sodium hyaluronate and quaternary ammonium compounds. \u003c\/span\u003e\u003cspan\u003esuch as benzalkonium chloride, which can lead to crystalline precipitation. Therefore, this product must never come into contact with surgical instruments or other products that contain these, or with \u003c\/span\u003e\u003cspan\u003eSolutions containing quaternary ammonium compounds as biocidal preservatives. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eDosage, type, and duration of use\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eThe prefilled syringe is to be removed from its packaging. The protective cap is to be removed from the Luer-Lock thread. A suitable sterile injection needle is to be screwed onto the syringe. The use of a single-use needle is recommended. Air should be evacuated from the needle before injection. The skin area intended for injection must be cleaned with an appropriate topical antiseptic. In the case of joint effusion, it is recommended that solutions containing quaternary ammonium compounds as biocidal preservatives be rinsed before injection. \u003c\/span\u003e\u003cspan\u003eKD Intra-Articular\u003c\/span\u003e\u003cspan\u003e® \u003c\/span\u003e\u003cspan\u003eGel \u003c\/span\u003e\u003cspan\u003einitially reduce the effusion by aspiration and examine it for bacterial etiology. The hydrogel can be injected 1 to 5 times at intervals determined by the physician. \u003c\/span\u003e\u003cspan\u003eInjected intra-articularly at intervals. The beneficial effects of a treatment last at least 6 months. Treatment cycles can be repeated if necessary.\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eDepending on the fill volume, several joints of a patient can be treated simultaneously. Unused product must be disposed of.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eDosage form\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eA box with one prefilled syringe of 1 ml - 4.8 ml.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eDurability\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eThe product must not be used after the expiration date. The expiration date (month\/year) is printed on the \u003c\/span\u003e\u003cspan\u003eSyringe blister and printed on the carton.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eStorage instructions\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eThe product should be stored dry between 2° and 25°C and protected from light and impact in the original packaging. Accordingly, warning symbols on the packaging must be observed.\u003cbr\u003eKeep the product out of reach of children.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eRecommended user group\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan\u003eIntended exclusively for use by physicians.\u003cbr\u003eFor single use only. Do not resterilize. Do not use syringes, needles, or hydrogel from open or damaged packaging or attempt to reseal packaging.\u003cbr\u003eSyringe content is non-toxic and non-flammable.\u003cbr\u003e\u003c\/span\u003e\u003cspan\u003eWhen using a product from damaged packaging or reusing with other \u003c\/span\u003e\u003cspan\u003epatients or the same patient at a different time are the intended properties and the \u003c\/span\u003e\u003cspan\u003eSterility is not guaranteed. Otherwise, possible transmission of material contamination and pathogens \u003c\/span\u003e\u003cspan\u003efrom the environment, the clinical area, or (other) patients could lead to health complications \u003c\/span\u003e\u003cspan\u003elead to. Resealing or resterilization does not constitute an allowed or guaranteed restoration of \u003c\/span\u003e\u003cspan\u003eusable condition.\u003cbr\u003eUnused syringes and their contents are not infectious and can be disposed of before or after the expiration date, observing national and local regulations. Used syringes and needles must be treated as epidemiologically hazardous waste, and national and local regulations for safe use and disposal must be followed.\u003c\/span\u003e\u003c\/p\u003e\n\u003cdiv class=\"page\" title=\"Page 1\"\u003e\n\u003cdiv class=\"section\"\u003e\n\u003cdiv class=\"layoutArea\"\u003e\n\u003cdiv class=\"column\"\u003e\n\u003cp\u003e\u003cspan\u003eStatus of information 05\/2021\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"ALBOMED GmbH","offers":[{"title":"Default Title","offer_id":47355873722708,"sku":"102","price":29.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0786\/8756\/8212\/files\/albomed-standard-albomed-gmbh-gelenkspritzen-stakonmed-488852.jpg?v=1772213626","url":"https:\/\/stakonmed.at\/en\/products\/albomed-standard-1-x-2ml","provider":"StakonMed","version":"1.0","type":"link"}